
Fishing for variants, genes and miRNAs in eye diseases
List of Publications
2025
Assane Rachidou MHA, Vanniarajan A, Kim U, Devarajan B. Analysing Differential Alternative Splicing Events and Their Impact on Retinoblastoma Progression Using RNA-seq Metadata. Asian Pacific Journal of Cancer Prevention. 2025;26:1781-92.
Dinesh S, Prajna L, Venkatesh PN, Dharmalingam K, Devarajan B. Fusarium spp. and Aspergillus flavus infection induces pathogen-specific and pathogen-independent host immune response in patients with fungal keratitis. Frontiers in Cellular and Infection Microbiology. 2025;15:1560628.
Mathan L, Prasad T, Aslam MH, Gr AT, Devarajan B, Prajna NV, et al. Genome-wide methylation analysis unveils genes and pathways with altered methylation profiles in pterygium. Experimental Eye Research. 2025;255:110353.
2024
Jeyaprakash K, Kumaran M, Kim U, Santhi R, Muthukkaruppan V, Devarajan B, et al. Investigating druggable kinases for targeted therapy in retinoblastoma. Journal of Human Genetics. 2024;69:467-74.
Kader MA, Devarajan B, Vijayan S, Ramakrishnan R, Sundaresan P, Uduman MS, et al. Myocilin mutation N480K leads to early onset juvenile and adult-onset primary open angle glaucoma in a Six generation family. Journal of Glaucoma. 2024;33:218-24.
2023
Swathi Chadalawada, SR.Rathinam, Prajna Lalitha, Naresh Babu Kannan, Bharanidharan Devarajan “ Detection of microRNAS expression signatures in vitreous humor of intraocular tuberculosis” Molecular Biology Reports Oct 2023 (IF: 2.3)
Kandasamy Kathirvel, Xiaochen Fan, Ravinarayanan Haribalaganesh, Devarajan Bharanidharan, Rajendrababu Sharmila, Ramasamy Krishnadas, Veerappan R Muthukkaruppan, Colin E. Willoughby and Srinivasan Senthilkumari “Small RNA Sequencing Reveals a Distinct MicroRNA Signature between Glucocorticoid Responder and Glucocorticoid Non-Responder Primary Human Trabecular Meshwork Cells after Dexamethasone Treatment” Genes 2023, 14, 2023 (IF: 4.1)
Gokulakrishnan Kuppan, Nikhil Joyappa, Viswanath Biju, Thirumoorthy Chinnasamy, Narasimhan Sandhya, Devarajan Bharanidharan, Joseph Ebin, David Arul Kevin Daniel, Sharma Sapna, Vasudevan Kavitha (2023). "Comparison of gut microbiome profile in patients with schizophrenia and healthy controls-A plausible non-invasive biomarker?" Journal of Psychiatric Research 162: 140-149. (IF: 5.25)
Kader, Mohideen Abdul*, Devarajan, Bharanidharan*, Vijayan, Saravanan, Ramakrishnan, Rengappa, Sundaresan, Periasamy, Uduman, Mohammed Sithiq, Krishnadas, Subbiah R, Kuppamuthu, Dharmalingam Kader (2023). "Myocilin Mutation N480K Leads to Early Onset Juvenile and Adult-onset Primary Open Angle Glaucoma in Six Generations of a Family." Journal of glaucoma: 10.1097. (* equally contributed) (IF: 2.0)
Kumaran, M. and Bharanidharan Devarajan (2023). "eyeVarP: a computational framework for the identification of pathogenic variants specific to eye disease." Genetics in Medicine: 100862. (IF: 8.9)
2022
Kalaimani, Lavanya, Bharanidharan Devarajan, Venkatesh Prajna Namperumalsamy, Muthukkaruppan Veerappan, Julie T. Daniels, and Gowri Priya Chidambaranathan. "Hsa-miR-143-3p inhibits Wnt-β-catenin and MAPK signaling in human corneal epithelial stem cells." Scientific reports 12, no. 1 (2022): 1-11. (IF: 4.9)
Kathirvel K, Lester K, Haribalaganesh R, Krishnadas R, Muthukkaruppan V, Lane B, Simpson DA, Goljanek-Whysall K, Sheridan C, Bharanidharan D, Willoughby CE, Senthilkumari S. Short and long-term effect of dexamethasone on the transcriptome profile of primary human trabecular meshwork cells in vitro. Sci Rep. 2022 May 18;12(1):8299. doi: 10.1038/s41598-022-12443-7. (IF: 4.9)
Kathirvel, Kandasamy, Ravinarayanan Haribalaganesh, Ramasamy Krishnadas, Veerappan Muthukkaruppan, Colin E. Willoughby, Devarajan Bharanidharan, and Srinivasan Senthilkumari. "A comparative genome-wide transcriptome analysis of glucocorticoid responder and non-responder primary human trabecular meshwork cells." Genes 13, no. 5 (2022): 882. (IF: 4.1)
Lavanya Kalaimani, Bharanidharan Devarajan, Venkatesh Prajna Namperumalsamy, Muthukkaruppan Veerappan, Julie T Daniels, Gowri Priya Chidambaranathan, “Hsa-miR-150-5p inhibits Wnt-β-catenin signaling in human corneal epithelial stem cells” Molecular Vision 2022; 28:178-191 (IF: 2.8)
U. Subramanian; B. Devarajan, Identification of dysregulated pathways and key genes in human retinal angiogenesis using microarray metadata, Gene Reports, 2022;26:101434. (IF: 1.3)
2021
Kandasamy, Kathirvel, Prajna Lalitha, and Bharanidharan Devarajan. "Comparative Analysis of non-coding smallRNAs in Pseudomonas aeruginosa Keratitis Strains with Different Antibiotic Susceptibility." bioRxiv (2021).
Shah, Mohd Hussain, Manojkumar Kumaran, Prakash Chermakani, Mohideen Abdul Kader, R. Ramakrishnan, Subbiah R. Krishnadas, Bharanidharan Devarajan, and Periasamy Sundaresan. "Whole-exome sequencing identifies multiple pathogenic variants in a large South Indian family with primary open-angle glaucoma." Indian Journal of Ophthalmology 69, no. 9 (2021): 2461. (IF: 1.9)
Kathirvel, Kandasamy, O. Rudhra, Siva Ganesa Karthikeyan Rajapandian, Namperumalsamy Venkatesh Prajna, Prajna Lalitha, and Bharanidharan Devarajan. "Characterization of antibiotic resistance and virulence genes of ocular methicillin-resistant Staphylococcus aureus strains through complete genome analysis." Experimental eye research 212 (2021): 108764. (IF: 3.5)
Chadalawada, Swathi, Kandasamy Kathirvel, Prajna Lalitha, S. R. Rathinam, and Bharanidharan Devarajan. "Dysregulated expression of microRNAs in aqueous humor from intraocular tuberculosis patients." Molecular Biology Reports (2021): 1-11. (IF: 2.3)
Susmita Chowdhury, Roopam Duvesh, Manojkumar Kumaran, Rupa Anjanamurthy, Jayant Kumar, Ayyasamy Vanniarajan, Bharanidharan Devarajan & Periasamy Sundaresan (2021) Clinical reassessments and whole-exome sequencing uncover novel BEST1 mutation associated with bestrophinopathy phenotype, Ophthalmic Genetics, DOI: 10.1080/13816810.2021.1998553 (IF: 1.8)
Viswarubhiny S, Anjanamurthy R, Vanniarajan A, Bharanidharan D, Perumalsamy V, Sundaresan P. Clinical exome sequencing facilitates the understanding of genetic heterogeneity in Leber congenital amaurosis patients with variable phenotype in southern India. Eye and Vision. 2021 Dec;8(1):1-1. (IF: 3.3)
2020
Gowri P, Kumar SM, Vanniarajan A, Bharanidharan D, Sundaresan P. A hospital-based five-year prospective study on the prevalence of Leber’s hereditary optic neuropathy with genetic confirmation. Molecular Vision. 2020;26:789. (IF: 2.9)
R. K. Raj; P. Dhoble; R. Anjanamurthy; P. Chermakani; M. Kumaran; B. Devarajan; P. Sundaresan. Genetic characterization of Stargardt clinical phenotype in South Indian patients using sanger and targeted sequencing. Eye and Vision. 2020;7(1):1-10. (IF: 3.3)
Kandasamy K, Thirumalmuthu K, Prajna NV, Lalitha P, Mohankumar V, Devarajan B. Comparative genomics of ocular Pseudomonas aeruginosa strains from keratitis patients with different clinical outcomes. Genomics. 2020;112(6):4769-76. (IF: 6.2)
Kalaimani L, Devarajan B, Subramanian U, Ayyasamy V, Namperumalsamy VP, Veerappan M, et al. MicroRNA Profiling of Highly Enriched Human Corneal Epithelial Stem Cells by Small RNA Sequencing. Scientific reports. 2020;10(1):1-10. (IF: 4.4)
2019
Thirumalmuthu K, Devarajan B, Prajna L, Mohankumar V. Mechanisms of fluoroquinolone and aminoglycoside resistance in keratitis-associated Pseudomonas aeruginosa. Microbial Drug Resistance. 2019;25(6):813-23. (IF: 3.4)
Kumaran M, Subramanian U, Devarajan B. Performance assessment of variant calling pipelines using human whole exome sequencing and simulated data. BMC bioinformatics. 2019;20(1):1-11. (IF: 3.3)
Khedekar A, Devarajan B, Ramasamy K, Muthukkaruppan V, Kim U. Smartphone-based application improves the detection of retinoblastoma. Eye. 2019;33(6):896-901. (IF: 3.8)
< 2015
Thirumalairaj K, Abraham A, Devarajan B, Gaikwad N, Kim U, Muthukkaruppan V, et al. A stepwise strategy for rapid and cost-effective RB1 screening in Indian retinoblastoma patients. Journal of human genetics. 2015;60(9):547-52. (IF:2.5)
Devarajan B, Prakash L, Kannan TR, Abraham AA, Kim U, Muthukkaruppan V, et al. Targeted next generation sequencing of RB1 gene for the molecular diagnosis of Retinoblastoma. BMC cancer. 2015;15(1):1-10. (IF:3.4)
Boomiraj H, Mohankumar V, Lalitha P, Devarajan B. Human corneal microRNA expression profile in fungal keratitis. Investigative ophthalmology & visual science. 2015;56(13):7939-46. (IF:3.5)
Velusamy N, Prakash L, Sivakumar N, Antony A, Prajna L, Mohankumar V, et al. Draft genome sequences of Staphylococcus aureus AMRF1 (ST22) and AMRF2 (ST672), ocular methicillin-resistant isolates. Genome announcements. 2014;2(2):e00168-14.
Jeganathan LP, Prakash L, Sivakumar N, Antony A, Alqarawi S, Prajna L, et al. Draft genome sequence of an invasive multidrug-resistant strain, Pseudomonas aeruginosa BK1, isolated from a keratitis patient. Genome announcements. 2014;2(2):e00153-14.
Mishra A, Devarajan B, Reardon ME, Dwivedi P, Krishnan V, Cisar JO, et al. Two autonomous structural modules in the fimbrial shaft adhesin FimA mediate Actinomyces interactions with streptococci and host cells during oral biofilm development. Molecular microbiology. 2011;81(5):1205-20. (IF: 4.82)
Bharanidharan D, Thiyagarajan S, Gautham N. Hexammineruthenium (III) ion interactions with Z-DNA. Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2007;63(12):1008-13. (IF: 0.65)
Bharanidharan D, Gautham N. Principal component analysis of DNA oligonucleotide structural data. Biochemical and biophysical research communications. 2006;340(4):1229-37. (IF: 3.06)
Bharanidharan D, Gautham N. Amino acid variation in cellular processes in 108 bacterial proteomes. Archives of microbiology. 2005;184(3):168-74. (IF:2.14)
Bharanidharan D, Bhargavi GR, Uthanumallian K, Gautham N. Correlations between nucleotide frequencies and amino acid composition in 115 bacterial species. Biochemical and biophysical research communications. 2004;315(4):1097-103. (IF:2.98)